PathXdxFrom tissue to slide

Research use only

Research pathology services

Histology, IHC, multiplex immunofluorescence, pathologist evaluation, and whole-slide scanning for preclinical, discovery, and translational programs. Share your study design and we'll tell you what's feasible, what it costs, and how long it takes before you commit.

Discuss your studySee the workflow

Capabilities

What we do

  • Multiplex immunofluorescence

    3–4 plex panels developed and optimized for your targets and tissue, delivered as one workflow rather than handed between vendors.

    • Panel design and antibody optimization
    • Staining and whole-slide fluorescence imaging
    • Panels for immune and tumor microenvironment markers
    • Several markers on one section when single-marker IHC isn't enough

  • Immunohistochemistry

    Single-plex chromogenic IHC across organ systems.

    • Routine and complex panels
    • Method development for new targets
    • Antibody optimization and protocol development

  • Histology

    Accessioning through sectioning and staining, for FFPE and frozen workflows.

    • Grossing, trimming, processing, and embedding
    • 4–5 µm sections on charged slides; custom thickness, serial, and step sections
    • H&E and special stains, with custom stain development
    • Tissue microarray construction

  • Pathologist evaluation

    Qualified pathologist assessment of research specimens, reported as research findings.

    • Standalone, or alongside any staining workflow
    • Research-use findings, not diagnostic interpretation

  • Whole-slide scanning

    Brightfield and fluorescence scanning on our own equipment, with whole-slide images (WSI) delivered to you for review, sharing, and your own analysis.

    • Brightfield and fluorescence whole-slide scanning
    • Whole-slide image files delivered to you
    • Digital slide archiving for your program

  • Tissue blocks

    Human FFPE tissue by indication, cell pellet blocks, and mouse tissue, plus blocks made from your own cells or animals.

    Browse tissue blocks

Workflow

From receipt to results

How specimens move through the lab, with every step recorded in our LIMS.

  1. 1

    Accessioning & intake

    Specimens logged in our LIMS, labeled, and QC'd on receipt, with every step recorded from there.

  2. 2

    Grossing, trimming & processing

    Dictation and trimming to your protocol; tissue processing for FFPE or frozen workflows.

  3. 3

    Embedding & sectioning

    Standard 4–5 µm sections on positively charged slides. Custom thickness, serial sections, and step sections on request.

  4. 4

    Staining

    H&E, special stains, single-plex IHC, or multiplex immunofluorescence, depending on your study.

  5. 5

    Whole-slide scanning

    Brightfield and fluorescence scanning on our own equipment. Whole-slide images are delivered to you and archived for your program.

  6. 6

    Pathologist evaluation

    Qualified pathologist assessment of research specimens where your study calls for it. Reported as research findings.

  7. 7

    Reporting

    Results delivered with methods documented, so your team can interpret and reproduce them.

Sample tracking

Every sample tracked in our LIMS

When you send us a study, each sample and slide is logged in our own laboratory information management system, from receipt to delivery.

  • Accessioned on arrival

    Each sample gets a unique ID, logged with species, tissue, and the services you ordered.

  • Labeled samples and slides

    Every sample and slide carries a printed label that matches its LIMS record.

  • Every step recorded

    Processing, sectioning, and staining steps are logged with who did them and when.

Sample record

Sample 03 · Mouse liver

In progress
  1. Received and accessionedlogged
  2. Processed and embeddedlogged
  3. Sectionedlogged
  4. Stained
  5. Scanned
Slide 01Slide 02Slide 03
Illustration

Expertise

Organ systems we support

Most tissue types are within scope. Working in an area not listed? Ask us.

  • Cardiology
  • Dermatology
  • Gastroenterology
  • Gynecology
  • Hematology
  • Musculoskeletal
  • Nephrology
  • Neurology
  • Ophthalmology
  • Otolaryngology
  • Urology
  • Special projects

Why PathXDx

High-touch partnership, owned imaging capability

  • Everything under one roof

    Histology, staining, and whole-slide scanning happen in our own lab. No pass-through vendors, no queue behind someone else's work, and one point of accountability from block to slide.

  • Multiplex without building it yourself

    Multiplex immunofluorescence takes real optimization to get right. We've done that work, so you don't need to stand up the capability internally for a single study.

  • A technologist who knows your protocol

    Named technologists are assigned to your program. They learn your tissue, your protocol, and your acceptance criteria.

  • Straight answers on scope

    If a study design won't produce the data you need, we say so before you commit, not after.

Ready to scope your study?

Tell us the tissue type, targets, study stage, and timeline. A technologist will help design the study and prepare a proposal.

Discuss your study